SPRAVATO® Therapy Quiz

SPRAVATO® is an FDA-approved nasal spray for adults with treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal thoughts. If traditional antidepressants haven’t worked, you may be a candidate for this innovative treatment, which provides rapid relief by targeting brain pathways differently than standard medications. SPRAVATO® can be used as a stand-alone treatment and/or an augmentation to your current psychiatric medication schedule. Discuss these options with your doctor.

What Is SPRAVATO®?

SPRAVATO® (esketamine) is a prescription nasal spray approved by the FDA for adults with treatment-resistant depression (TRD) and for those with major depressive disorder (MDD) who are experiencing suicidal thoughts or behaviors. Unlike traditional antidepressants that target serotonin or other neurotransmitters, SPRAVATO® works on the brain’s glutamate system to help restore neural connections disrupted by depression. Administered in a certified medical setting under supervision, SPRAVATO® is designed to work alongside an oral antidepressant, offering a fast-acting option for individuals who haven’t found relief with conventional treatments.

How Is SPRAVATO® Administered?

SPRAVATO® is administered as a nasal spray in a certified medical office under the supervision of a healthcare provider. After a treatment-resistant depression assessment, your provider will determine whether SPRAVATO® is appropriate for you. If you’re a candidate, a personalized care plan will be developed to guide your treatment. During each session, the medication is self-administered under clinical observation, and patients remain on-site for a few hours for monitoring before being cleared to leave. This structured approach ensures safety and supports the effectiveness of your ongoing care.

Is SPRAVATO® Safe?

SPRAVATO® is considered safe for many individuals when used as prescribed and under medical supervision. Like all medications, it carries potential risks and side effects, so a proper clinical evaluation is essential before starting treatment. This evaluation helps determine if SPRAVATO® is appropriate for your health profile, particularly if you have conditions such as high blood pressure, a history of substance use, or specific heart issues. When administered in a certified setting with professional monitoring, SPRAVATO® offers a controlled and effective option for addressing treatment-resistant depression.

Am I a Candidate for SPRAVATO® Therapy?

5 Questions to Ask Yourself

Are you experiencing chronic symptoms of depression that haven't improved with standard treatments?

If your symptoms have persisted despite trying prescription medicine, you may be dealing with treatment-resistant depression. SPRAVATO® is specifically designed for adults facing chronic symptoms that haven’t responded to traditional antidepressants.

Have you been diagnosed with a specific mental disorder, such as MDD?

SPRAVATO® is approved for individuals with a specific mental disorder like MDD, especially when accompanied by suicidal thoughts or when other treatments have failed. A comprehensive assessment by a qualified healthcare provider can determine if this therapy is right for you.

Are you currently in individual or group counseling but still not meeting your mental health goals?

While therapy is a valuable part of mental health care, it may not be enough on its own. If you’ve been working through individual or group counseling but feel stuck, SPRAVATO® may help you move closer to your mental health goals.

Have prescription medicine or lifestyle changes failed to bring lasting relief?

If you’ve tried prescription medicine and made lifestyle changes, such as improving sleep, diet, or exercise, without significant or lasting improvement, SPRAVATO® could offer an alternative approach that works differently in the brain.

Has social isolation become a part of your life due to depression?

When depression leads to social isolation or withdrawal from friends and family, it can be a sign that more intensive treatment is needed. SPRAVATO® may help reduce symptoms so you can reconnect and re-engage with the people and activities you care about.

Find a SPRAVATO® Clinic Near You

Our compassionate team is here to guide you every step of the way. We’ll reach out to answer your questions, discuss your options, and help you take the next step toward feeling better.

Not sure yet? No problem! We’ll send you more information about how SPRAVATO® can help. Keep an eye on your inbox!